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Home page › Louis Widmer › Ingredients › Urea

Urea – valuable active
ingredient for dry
and irritated skin
Natural moisture retention factor
- End product of the amino acid change in the urea cycle of plants and animals
- In the horny layer of the epidermis in humans
- Primarily involved in regulating the water balance in the horny layer
- Accounts for around 7% of the natural moisture retention factors in healthy skin
- In atopic patients, affected areas contain only one fifth of the normal amount of urea
- In psoriasis patients, the content is reduced by up to 40% in the areas of the lesions
Characteristics and effectiveness of urea, also called carbamide

Remederm preparation with urea
Urea is used at a concentration of 3% to 5% in the following six Remederm preparations due to its high water retention properties: